October 9, 2009

Improvements from consuming a paleolithic, hunter-gatherer type diet – European Journal of Clinical Nutrition (2009)

Filed under: Uncategorized — SL @ 10:53 pm

L A Frassetto, M Schloetter, M Mietus-Synder, R C Morris Jr and A Sebastian (2009)

Metabolic and physiologic improvements from consuming a paleolithic, hunter-gatherer type

diet. European Journal of Clinical Nutrition (2009) 63, 947–955; doi:10.1038/ejcn.2009.4; published online 11 February 2009.

Summary of paper by W.Long:

"A study published in the European Journal of Clinical Nutrition acknowledged that the contemporary American diet fuels numerous chronic diseases. The study then compared the results of participants eating their usual diet with the effects of changing to a paleolithic diet. The paleolithic diet provided metabolic and physiologic improvements in a matter of days.

How participants changed their diet

Nine sedentary, but not obese, healthy volunteers joined a metabolically-controlled study as outpatients. Their weight was checked daily to ensure there was no weight loss.

The participants first ate as usual for 3 days. Then, for 7 days, they consumed three ramp-up diets that increased potassium and fiber. They finished the study by eating a paleolithic diet of lean meats, fruits, vegetables and nuts for 10 days.

What the study measured

In all of the following measured variables, either eight or all nine participants had identical directional responses when eating a paleolithic diet. The study looked at:

  • Arterial blood pressure (BP)

  • 24-hour urine sodium and potassium excretion

  • Plasma glucose and insulin areas under the curve (AUC) during a two-hour oral glucose tolerance test (OGTT). The glycemic index of a food is defined as the area under the two-hour blood glucose response curve (AUC) following the ingestion of a fixed portion of carbohydrate (usually 50 g).

  • Insulin sensitivity, which generally shows the risk for heart problems

  • Plasma lipid concentrations, which are also used to determine the risk of coronary heart disease, and

  • Brachial artery (the major blood vessel of the upper arm) reactivity in response to ischemia (a restriction in blood supply)

The improvements in health

Compared with the participants’ usual diet, even short-term consumption of a paleolithic diet provided:

  • Significant reductions in BP associated with improved arterial distensibility

  • Significant reductions in plasma insulin versus time AUC during the OGTT, and

  • Large significant reductions in total cholesterol, low-density lipoproteins (LDL) and triglycerides

Help yourself

Improve blood pressure

High blood pressure can remain undetected for years, but it can damage blood vessels, and increase the risk of heart attack and stroke. This study showed that consuming the Paleo Diet can improve blood pressure in less than two weeks. Furthermore, studies of hunter-gatherer cultures have shown no age-related rise in blood pressure, a process that is normally considered to be a universal aspect of aging.2

Fight diabetes and cardiovascular disease

You can also use this diet to improve glucose tolerance, decrease insulin secretion, and increase insulin sensitivity, as this study found. Impaired glucose tolerance is seen as a pre-diabetic state that is associated with increased risk of cardiovascular pathology. Insulin sensitivity is also used to measure the risk for heart disease. Generally, greater insulin sensitivity indicates reduced risk of heart problems.

Reduce risk of atherosclerois

The Paleo Diet also improved lipid profiles very quickly for healthy, sedentary people. Lipid profiles show total cholesterol, LDL-C that is referred to as “bad” cholesterol, triglycerides, and “good” cholesterol or HDL-C.

Improving your lipid profiles can reduce your risk for heart attack and stroke caused by blood vessel blockage or hardening of the arteries, also known as atherosclerois".


Posted via email from sl26mi


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